Living with multiple sclerosis (MS) means navigating not only symptoms and treatments, but also lifestyle choices that can influence the course of the disease. One of the most powerful—and often overlooked—factors is diet. A recent review published in Nutrients (MDPI, 2024) highlights how the foods we eat can either fuel inflammation or help calm it, shaping the progression of MS.
Why Diet Matters in MS
MS is an autoimmune condition where the immune system attacks the protective covering of nerves. While genetics play a role, environmental factors—especially nutrition—can tip the balance between inflammation and healing. Researchers now see the gut–brain axis (the connection between gut health and the nervous system) as a key player in MS.
Fats: The Good, the Bad, and the Protective
Saturated fats (found in fatty meats, butter, coconut cream/milk, processed foods) tend to worsen inflammation and are linked to more active MS.
Monounsaturated fats (like olive oil and avocados) help reduce oxidative stress and support gut health.
Omega-3 fatty acids (from fish, flaxseed, walnuts) are strongly anti-inflammatory and may lower MS risk and improve outcomes.
Trans fats & ultra-processed foods disrupt gut bacteria and fuel inflammation.
Carbohydrates: Quality Counts
Refined sugars and white flour spike blood sugar and drive inflammation.
Whole grains and complex carbs provide steady energy and support gut health.
Fiber is especially important—it feeds beneficial gut bacteria that produce short-chain fatty acids (SCFAs), which strengthen the gut lining and calm the immune system.
Proteins: A Mixed Picture
Red and processed meats may promote inflammation.
Dairy and gluten show mixed evidence—some people report sensitivity, but research is not conclusive.
Plant proteins (beans, lentils, soy) are generally more supportive of an anti-inflammatory diet.
Fiber: A Star Player
Fiber-rich foods (vegetables, fruits, legumes, whole grains) consistently show protective effects in MS. By nourishing gut bacteria, fiber helps produce SCFAs that:
Strengthen the gut barrier
Reduce harmful immune activity
Support regulatory T cells (which keep inflammation in check)
Gut Microbiota: The Hidden Link
People with MS often show gut dysbiosis—an imbalance in gut bacteria. Diet is one of the strongest ways to restore balance. Eating more fiber, omega-3s, and plant-based foods helps cultivate a healthier microbiome, which in turn reduces inflammation in the brain and spinal cord.
Practical Takeaways
If you’re living with MS, consider these dietary shifts:
Favor: olive oil, fatty fish, nuts, seeds, whole grains, legumes, fruits, vegetables
Limit: saturated fats (butter, fatty meats, coconut cream/milk), refined carbs, sugary foods, ultra-processed snacks
Final Word
This research reinforces what many people with MS already sense: food matters. While diet isn’t a cure, it’s a powerful tool to support your body, reduce inflammation, and potentially slow disease progression. More clinical trials are needed, but the evidence so far points toward an anti-inflammatory, fiber-rich diet as a smart choice for living well with MS.
SOURCE: Read the full research
Early symptoms and the Specific Risk of Multiple Sclerosis
A promising path for future treatments to stop progressive MS
Manganese benefits for autoimmune disease


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