Novel Paradigm Connecting MS to Hygiene Hypothesis, Microbiome

Newsroom – Published on: January 05, 2020 

Researchers investigate Novel Paradigm 

Connecting Multiple Sclerosis to Hygiene Hypothesis, 

Microbiome.

The researchers had hypothesized that the microbiome in 

MS represents a defective environment that does not provide normal levels of toll-like receptor (TLR2)-tolerizing bacterial products to the systemic immune system.

CONCLUSION:  that this may be a new approach to treating MS by inhibiting autoimmune inflammation while facilitating myelin repair.

Multiple Sclerosis attacks the central nervous system - brain and spinal cord -  interfering with the nervous system signals and causing neurological symptoms. 

Symptoms may include numbness, tingling, pain, burning, and visual disturbances, tremor, difficulty walking, lack of coordination and constipation.
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In this short 3 minute video Harvard Associate Professor Curtis Huttenhower talks about the Human Microbiome Project and the role that microbes—organisms like bacteria, viruses, and fungi that live in the stomach, in the mouth, on the skin, or elsewhere—play in normal bodily functions, like development or immunity, as well as in disease.