Psoriasis and the role of fibroblast growth factors in metabolic pathways.

Psoriasis is a common and chronic inflammatory skin disease whose exact pathogenesis remains uncertain and continues to be a topic of extensive research. Nowadays, research focuses not only on understanding the genesis of skin lesions but especially on the explanation of systemic disorders associated with psoriasis.

This is the first prospective study assessing serum concentrations of FGF21 and FGF23 in psoriatic patients and adds value by evaluating the relationships with systemic medications such as acitretin or methotrexate.

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